This transport system appears to continue to work even when regular DHA transport is impaired. The link between Covid and Vitamin D deficiency hasn't been studied, but Dr. Patrick has theorizing that due to Covid entering from the ace2 receptor and Vitamin D deficiency has been shown to lead to problems with the ace2 receptors functioning. Other foods high in magnesium include avocados, almonds, oats and peanut butter (see full list here). The most recent guest on the hugely popular The Joe Rogan Experience is Rhonda Patrick PhD, a cell biologist whose work focuses on promoting a healthier, longer lifespan. Dr Rhonda Patrick has popularised the use of vitamin D as a supplement and arguably the original proponent of fasting that reached the MMA community. Broq is manufactured by the same company as Prostaphane, for the US market. I could just strike them from the list, but I think for some this list (and the rationales) may be of interest. In the mornings she limits herself to just 1 coffee, to which she sometimes adds the Lairds mushroom blend mentioned above. "I think vitamin D really is the star potentially."- stated on Joe Rogan before millions, May 2020 Dr. Rhonda Patrick Goes In Depth on the Benefits of Vitamin D 2,659,516 views May 14, 2020 Its a higher dose per serving (750mg vs 500mg), which is based off clinical studies26Cocoa flavanol consumption improves cognitive function, blood pressure control, and metabolic profile in elderly subjects: the Cocoa, Cognition, and Aging (CoCoA) Studya randomized controlled trial Mastroiacovo et al. She notes that exercise is better at preventing type 2 diabetes than metformin, citing a randomized controlled trial involving 3,200 people44Reduction in the Incidence of Type 2 Diabetes with Lifestyle Intervention or Metformin Diabetes Prevention Program Research Group (2002). Quercetin - added recently. She co-ordinates her supplementation with Vitamin D blood testing, so that she stays between 40 and 60 ng/ml, generally hovering around 50 ng/ml. Vegetarian / Vegan Fish Oil Alternatives? If she misses a dose in the morning then she will typically double up in the evening. She says her interest in resveratrol stems mainly from preliminary clinical trials showing positive benefits in cognition for older and cognitively impaired adults, including: Her current reservation is around a study that showed 250mg/day of resveratrol blunted the positive effects of exercise42Resveratrol blunts the positive effects of exercise training on cardiovascular health in aged men Gliemann et al (2013). Joe uses the sauna 7 days/week, 180-degrees for 25 min. For example, as an Amazon Associate, I earn from qualifying purchases. According to Rhonda, omega-3 phospholipids are found in fish, and in greatest concentration in fish roe (fish eggs). Last week, Elysium sponsored the show and Rogan said the following. (2008)36Probiotics: progress toward novel therapies for intestinal diseases Yan et al. The aspect of melatonin production decreasing with age is important (see this study for more discussion). Fish Oil DHA and EPA. The full extent of vitamin's D impact has yet to be fully understoodnearly every cell and tissue in our body has vitamin D receptors (proteins that bind to vitamin D); and in its active form, vitamin D can interact with the vast majority of the body's cells. In her Dec 2019 Q&A discussion, she discussed Resveratrol, saying that she doesnt take it currently, but is considering taking it. BeWellBuzz. It has a host of potential benefits, including: The bioavailability of curcumin can be increased with the addition of fat and a component of black pepper called piperine. There are studies showing that any people in the US (and the world) are low in vitamin D. It's one of the most affordable supplements when comparing to other ones. Rhonda suggests that melatonin can be useful as we age (particularly for those 50+), because over time our natural production decreases. March 15, 2022. Rhondas Pregnancy, Breastfeeding & Toddler Supplements. Rhonda uses the sauna 5 days/week, 180-degrees for 25 min. . | 2015 | Investigative Ophthalmology & Visual Science. Below well look at the micronutrient contents of the two multivitamins Rhonda alternates between: Its worth noting that the US version of ONE is formulated slightly differently to the UK version. (2016). Vitamin K2 on the other hand is found in fermented foods, which are less common in a western diet. (2017). OmegaQuant was founded by Bill Harris who Rhonda interviewed recently. Which vitamin D does Joe Rogan take and how much? Whilst supplementing omega-3s is a daily occurrence for Rhonda, she also adds salmon roe caviar a few times per week. Rhonda doesnt take Athletic Greens, and nor has she in the past. | 2014 | Clinical Nutrition. PQQ is a compound found in plants that has been found to decrease inflammation and improve mitochondrial efficacy in humans.32Dietary pyrroloquinoline quinone (PQQ) alters indicators of inflammation and mitochondrial-related metabolism in human subjects Harris et al (2013). For more info on turmeric and lead chromate, see these studies: Rhonda continues to utilize turmeric in its organic form (which doesnt have lead chromate added) both as juices and in smoothies. At one stage she was taking Visbiome probiotics every few weeks, to top up her healthy gut bacteria. Rogan was wowed by the evidence Patrick offered, suggesting that vitamin D status has a profound impact on COVID-19 outcomes. Joe Rogan's Daily Vitamin & Minerals: Omega-3 Fish Oil - Carlson Omega-3 Fish Oil. ApoE4 increases Alzheimers risk between 2-3x if youve 1 allele and 15x with 2 alleles. Then, if she wants an extra boost, she will make the nootropic drink. It contains: She says its like dynamite for the brain, and she feels on fire with it . Smoothies are great because they are easy to make, quick to consume and are packed with nutrients. Fasting Mimicking Diet has been shown to improve symptoms of multiple sclerosis So where does the vitamin K2 supplementation come in? For Zeaxanthin, according to this paper17Zeaxanthin: Review of Toxicological Data and Acceptable Daily Intake James Edwards | 2016 | Journal of Ophthalmology, the EU put an upper use level of 2 mg / day. Close. Micronutrients, a subset of which are referred to as vitamins and minerals, are regarded as essential if experiments show that humans get sick in their absence. Whereas the Thorne multivitamin contains 140 mcg of Lutein and zero Zeaxanthin. Consuming this in addition to her regular omega-3 supplementation. For extensive details, see this separate post where we look at what sulforaphane is, why its important, and the various forms Rhonda consumes it in, including self-grown broccoli sprouts. Its also worth noting that her Luteolin supplement, discussed below, contains a calcium ascorbate blend of vitamin C that results in 68 mg of additional vitamin C. Lutein and Zeaxanthin are yellow and orange pigments, also known as carotenoids, that are found in fruit and vegetables. However, for people who dont exercise, then the use of metformin may warrant further inspection. Dec 22, 2022. As of yet, Rhonda hasnt come back to taking Nicotinamide Riboside, and has said she is waiting for more human research to be completed. Rogan himself did call out Asprey's misinformation on his podcast, saying in episode #459 with Dr. Rhonda Patrick that "he gets s--- wrong and I don't know if he's always so good at recognizing . Joe Rogan has always been open about his supplementation and health regiment. With a PhD in biomedical science and a Bachelor's of Science degree in biochemistry/chemistry she is an expert and vocal spokesperson for health research. She adjusts her supplements over time, and this post is kept continually updated. Noting it also doubles as a (weak) alternative to painkillers. In this next section well look at the supplements Rhonda takes in the evenings. 1 cup of blueberries (fresh or frozen) 1 tall shot glass of flaxseed (optional) Note: Rhonda doesn't drink all the 64 fl oz of her ultimate micronutrient smoothie every morning but usually shares it with her husband. Below, vitamin D expert, Rhonda Patrick, Ph.D., shares the latest research on . So far weve covered supplements that Rhonda has said she takes on a daily basis. The supplements that Joe Rogan takes include vitamins, fish oil, protein, pre-workout, nootropics, probiotics, and more. For more on David Sinclair and the supplements he takes, including Resveratrol and NMN, see this separate post. . Vitamin K2 - Thorne Research K2/D3 Drops: One drop every two to three days. If youve got any queries on the above, please leave them below in the comments. Firstly, this crowd sponsored support allows her to continue to work independently, without being reliant on sponsors or grants. In this episode, I talk about how Joe Rogan recently lashed out at the agricultural scientist Kevin Folta when Kevin discussed an alternative interpretation of the scientific data that was different t. - Listen to Joe Rogan LASHES OUT at Kevin Folta about Monsanto's glyphosate, gets DEBUNKED by Rhonda Patrick's mentor by The Kevin Bass Show instantly on your tablet, phone or browser - no . The nicotinamide riboside product she was taking before was called Thorne NiaCel (now discontinued) which contained Nicotinamide Riboside Chloride made by Chromadex. Joe Rogan has interviewed . Quercetin is an antioxidant that supports a healthy immune system and clears out senescent cells which help to prevent any age-related diseases from developing. Approximately 1/2 the US population are thought to be deficient in magnesium28Suboptimal magnesium status in the United States: are the health consequences underestimated? We know that good sleep is absolutely crucial to overall health, so if we can supplement melatonin and measure a noticeable positive impact on sleep, thats a big (easy) win. Vitamin K1, once absorbed by the body, is prioritized for use in the liver to produce proteins essential for blood clotting. She adds a couple of important caveats: In terms of an estimate on dosage for the Lions Mane, Rhonda cites a study (source) that showed significant improvements in cognitive function after 8 weeks of 3g per day vs placebo for 50-80 year olds with existing cognitive impairment. However, for example with her mother, who doesnt eat as many green vegetables, she encourages a larger supplemental dose. Related to curcumin, Rhonda discussed the herb its derived from, Turmeric, in an Instagram post (link). Rhonda currently supplements vitamin K on the basis that its an insurance policy, in case she doesnt get enough K from vegetables. Dr Rhonda Patrick is one of my all time favorite guests and absolutely one of the most brilliant people I know. "This episode of the podcast is [] She avoids using a dairy creamer, because dairy contains a protein that can inhibit the flavonoids in the cocoa. Rhonda supplements 10 mg of Lutein and 2 mg of Zeaxanthin daily, via a product called Pure Encapsulations Lutein & Zeaxanthin. Covering her multivitamin, vitamin D, Omega-3 fish oil, K2, Magnesium, Probiotics, PQQ, Curcumin, Collagen, Sulforaphane, Choline, Lion's Mane Mushroom and more. She opts for the salmon roe rather than supplements, as its a potent, fresh source of phospholipids (~438 mg of EPA and ~514 mg of DHA per ounce). In an Instagram post (link) Rhonda mentions studies have shown that many cocoa products have high levels of cadmium and lead25Cadmium and lead in cocoa powder and chocolate products in the US Market Abt et al (2017). Sweat contains metals from plasma and dermal layers, implying it is a mode of excretion for dietary and occupational exposures. The specific figure of around 10 mg likely comes from a string of research papers on sleep disruption, where ~9mg was the dose used. Below summarizes the details: VSL #3 was originally created by Professor Claudio De Simone, and produced by VSL Inc. All the clinical studies before 2016 were performed on the original formula of VSL#3. Of those, choline and molybdenum are essential micronutrients. Thorne contains magnesium, copper, calcium and gamma tocopherol, whilst ONE does not. Rhonda currently gets her omega-3 phospholipids from wild salmon roe caviar. Many of those enzymes have to do with energy production and energy utilization. Omega-3 Phospholipids, Alzheimers & APOE4. Rhonda mentioned in her February 2023 Q&A that shes continuing to take Life Extension- PQQ 20mg Caps. She has mentioned previously that this high dosing of omega-3s is somewhat experimental as studies on the benefits usually use lower daily dosages. Rhonda Perciavalle Patrick has a Ph.D. in biomedical science from the University of Tennessee Health Science Center, Memphis TN, and St. Jude Children's Research Hospital, Memphis, TN. Fish oil is a supplement Rogan has mentioned he takes daily. Presumably she then tops up using vitamin D capsules. | 2017 | European Journal of Nutrition. Nootropics are products aimed at improving cognitive function, and in Rhondas June 2021 members Q&A she updated us on her preferred nootropic, which she consumes in the form of a drink. Rhondas keen interest in omega-3 phospholipids stems from having 1 ApoE4 allele in her DNA. When that task is satisfied, then the level of K1 increases in the blood, and helps to transport calcium for use around the body. Fortunately it doesnt require much blood, just single drop onto a piece of card, which you then post back. I mention this section because for some people Visbiome is hard to get hold of, and up until now, it was thought VSL #3 was a satisfactory alternative. View this post on Instagram. It contains an isothiocynate with very similar properties to sulforaphane, called Moringin. Its a blend of magnesium gluconate, magnesium acetyl taurinate and magnesium citrate, coupled with l-theanine. De-prioritizing other functions, such as those that could aid in longevity. The first video on JRE received over 2.5 million views. Rhonda pointed to a possible link between low vitamin D levels, and increased severity of Covid-19 disease. This amplifies the importance of choosing a supplement that you can rely upon. ncbi.nlm.nih.gov. She suggests the optimal range is a blood concentration between 40 - 60 ng/ml. Whereas we can get adequate amounts of most micro nutrients through our diet, its hard to do that with vitamin D. Instead our bodies rely upon UV-B light from the sun, which we dont always get enough of, making supplementation important. Theres a little monk fruit too, which sweetens the mixture. Dr. Rhonda Patrick has been making waves in the field of healthy aging. Due to the amount of magnesium needed in supplements, it isnt really practical for multivitamins to cover it. . See this detailed post for the details on which supplements Rhonda took during pregnancy and breastfeeding. As many are already aware, calcium is crucial to healthy bones, but also regulates muscle contraction, nerve conduction, blood clotting and more. And, much of the conversation focused on the sunshine vitamin! However, another study using 500mg showed synergistic effects in combination with exercise43Resveratrol Enhances Exercise-Induced Cellular and Functional Adaptations of Skeletal Muscle in Older Men and Women Alway et al. Below well look at supplements Rhonda used during her pregnancy (a section which, of course, wont be applicable to all). She has done extensive research on aging, metabolism, nutrition, and cancer. Rhondas Dosage: 2 tablets (20 mg total) of BROQ each morning, after a meal. 3 grams of high-DHA Norwegian PURE-3 fish oil daily (6 pills) and high-EPA Norwegian PURE-3 fish oil. She consumes it by adding it to her smoothies, coffee and sometimes tea. Of course, more isnt always better. She mentioned this specifically on Joe Rogan podcast #1474, and then more recently in her July 2022 Q&A. In addition, the supplement also has 50 mg of quercetin and 100 mg of rutin both flavonoids with potential health benefits. Its estimated that around 25% of the population have at least 1 ApoE4 allele. Her ONE multivitamin already contains 3 mg of Lutein and 0.5 mg of Zeaxanthin. Especially when compared to the stringent regulations that are imposed on the pharmaceutical industry. It may have seemed unusual for him to speak of sensory deprivation tanks in such a way, but it was no the last word - he semiregularly . Vitamin D - Thorne Research - D3 5,000iu. Thornes contains much less lutein and. Joe Rogan Experience - Best of the Week of December 17, 2017 JRE #1054 - Dr. Rhonda Patrick - JRE #1055 - Bret Weinstein - edited by Mischief Makers Productions - ( intro by . It is noticeably expensive, even for ubiquinol. A study, 200mg/daily resveratrol supplementation improved healthy 50-75 year olds memory recall, In another study, patients with alzheimers disease who took resveratrol saw improvements in cognition, and decreases in biomarkers of Alzheimers disease and inflammation, Reduction in gaining lean muscle mass whilst on an exercise program, compared to placebo, Inhibition of mitochondrial adaptations and improvements in cardiorespiratory fitness by 50 percent and diminished whole-body insulin sensitivity after aerobic exercise, Notes on many of the key things Rhonda has discussed about, Notes on the supplements Rhonda is giving to her, now, toddler (. #1474 - Dr. Rhonda Patrick The Joe Rogan Experience 125 Clips. For a bigger version of this table with more products and details, see this spreadsheet. Rhonda currently takes a sulforaphane supplement called BROQ. Populations with vitamin D deficiency at high risk for COVID-19 mortality. After trying a number of fish oil supplements, and noticing I prefer them without added flavoring, Im personally using Viva Naturals Triple Strength. Rhonda added Moringa powder to her diet after research from Jed Fahey at Johns Hopkins University. Rhonda notes in her recent Joe Rogan interview (#1701) shes a proponent of whats called the omega-3 index test. See Rhondas Instagram post on collagen for more info. The version Rhondas taking (ubiquinol) is proposed to be more bio-available than ubiquinone18Increased Bioavailability of Ubiquinol Compared to Ubiquinone Aoki et al. If you'd like to receive very occasional emails about updates to the site, please sign up below: We've sent you an email - please open it and click confirm to receive email updates. As of Rhondas January 2023 Q&A she is still takin CocoaVia. See Rhondas research section on metformin for more info. That said, its still relatively under studied compared to other supplements. Top Moments. If youre looking for further Rhonda Patrick related content, below are some related posts Ive written: For those curious, see this post for a log of the main updates over time. A source thats particularly high in K2 are fermented soya beans, also known as natto in Japan. Mentioning that higher levels are associated with a lower risk of all-cause mortality8Blood n-3 fatty acid levels and total and cause-specific mortality from 17 prospective studies Harris et al. I'm being deadly serious,I want to see these freaks of nature super charged. This paper suggests there is strong evidence that up to 20 mg / day of Lutein is safe16Dietary guidance for lutein: consideration for intake recommendations is scientifically supported Ranard et al. Rhondas early mentor, Bruce Ames, researched what happens when our bodies have insufficient levels of micronutrients, and found that our bodies prioritize the scarce nutrients for functions related to survival and reproduction. Namely: So when it comes to healthy individuals who exercise, she doesnt see any synergy with the use of metformin for improving healthspan and lifespan. when asked on Joe Rogan's podcast how vegetarians can supplement EPA & DHA, . However whilst pregnant, Rhonda stopped taking any non-essential supplements (including Nicotinamide Riboside) that could pose even the slightest risk to her child. 1 apple. If instead you view via a web browser, then the comment isnt at the top, and it may be hard to locate. Archived. How much vitamin D does Dr. Rhonda Patrick recommend daily? It comes in 2 different forms, vitamin K1 (phylloquinone) and K2 (menaquinone). In a non supplemented vegetarian/vegan diet, the primary source of omega-3 fatty acids comes from alpha linolenic acid (ALA), which is found in various plants (particularly flaxseed). In a podcast with Kevin Rose (Jan 2020 link), Rhonda discussed the use of metformin for longevity. - A study in Indonesia found that out of the patients that died from COVID-19, 98.9% of them were deficient in vitamin D, while only 4% of the . Instead, consider: omega-3, glutamine, magnesium, calcium (if concerned about bone injury), vitamin D, and tart cherry juice for persistent soreness Introduction Dr. Andy Galpin ( @DrAndyGalpin ), Professor of Kinesiology at California State University, Fullerton, and one of the foremost experts in the world on the science and application of . For context, the RDA for adult women is 425 mg/day. Rhonda has had David Sinclair on the podcast discussing the positive effects of Resveratrol. Luteolin: A Flavonoid that Has Multiple Cardio-Protective Effects and Its Molecular Mechanisms, Luteolin suppresses inflammation-associated gene expression by blocking NF-B and AP-1 activation pathway in mouse alveolar macrophages, Luteolin Promotes Cell Apoptosis by Inducing Autophagy in Hepatocellular Carcinoma, Dietary pyrroloquinoline quinone (PQQ) alters indicators of inflammation and mitochondrial-related metabolism in human subjects, Effect of the Antioxidant Supplement Pyrroloquinoline Quinone Disodium Salt (BioPQQ) on Cognitive Functions, Add-on Treatment with Curcumin Has Antidepressive Effects in Thai Patients with Major Depression: Results of a Randomized Double-Blind Placebo-Controlled Study, Pure Encapsulations Phosphatidylcholine, Mechanisms of probiotic action: Implications for therapeutic applications in inflammatory bowel diseases, Probiotics: progress toward novel therapies for intestinal diseases, P884 No shared mechanisms among old and new VSL#3: Implications for claims and guidelines, Mfsd2a is a transporter for the essential omega-3 fatty acid docosahexaenoic acid, Effects of Resveratrol on Memory Performance, Hippocampal Functional Connectivity, and Glucose Metabolism in Healthy Older Adults, Resveratrol regulates neuro-inflammation and induces adaptive immunity in Alzheimers disease, Resveratrol blunts the positive effects of exercise training on cardiovascular health in aged men, Resveratrol Enhances Exercise-Induced Cellular and Functional Adaptations of Skeletal Muscle in Older Men and Women, Reduction in the Incidence of Type 2 Diabetes with Lifestyle Intervention or Metformin, Metformin blunts muscle hypertrophy in response to progressive resistance exercise training in older adults: A randomized, doubleblind, placebocontrolled, multicenter trial: The MASTERS trial, Metformin inhibits mitochondrial adaptations to aerobic exercise training in older adults, Andrew Huberman Supplements Full List Deep Dive Into What & Why, David Sinclair Supplements List Deep Dive into What & Why (2023), Rhonda Patrick Supplements List Updated February 2023, Andrew Huberman Diet and Routine What He Eats & Why, Andrew Huberman Book Recommendations 25 He Recommends & Why, Joe Rogan Supplements List What He Takes & Why 2023.